Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide

The major proteins in isolated synaptic junctions (SJs) and postsynaptic densities (PSDs) have been compared to actin, tubulin, and the major neurofilament (NF) protein by two-dimensional gel electrophoresis and tryptic peptide map analysis. These studies show: (a) tubulin is present in SJ and PSD f...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1978
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110230/
https://www.ncbi.nlm.nih.gov/pubmed/568145
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description The major proteins in isolated synaptic junctions (SJs) and postsynaptic densities (PSDs) have been compared to actin, tubulin, and the major neurofilament (NF) protein by two-dimensional gel electrophoresis and tryptic peptide map analysis. These studies show: (a) tubulin is present in SJ and PSD fractions and is identical to cytoplasmic tubulin, (b) actin in these fractions is very similar to the gamma- and beta-actin found predominantly in nonmuscle cells, and (c) the major PSD protein is distinct from all other known fibrous proteins.
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spelling pubmed-21102302008-05-01 Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide J Cell Biol Articles The major proteins in isolated synaptic junctions (SJs) and postsynaptic densities (PSDs) have been compared to actin, tubulin, and the major neurofilament (NF) protein by two-dimensional gel electrophoresis and tryptic peptide map analysis. These studies show: (a) tubulin is present in SJ and PSD fractions and is identical to cytoplasmic tubulin, (b) actin in these fractions is very similar to the gamma- and beta-actin found predominantly in nonmuscle cells, and (c) the major PSD protein is distinct from all other known fibrous proteins. The Rockefeller University Press 1978-10-01 /pmc/articles/PMC2110230/ /pubmed/568145 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide
title Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide
title_full Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide
title_fullStr Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide
title_full_unstemmed Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide
title_short Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide
title_sort synaptic proteins. characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110230/
https://www.ncbi.nlm.nih.gov/pubmed/568145

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