Fibroblasts and macrophages of mice with the Chediak-Higashi-like syndrome have microtubules and actin cables

Cells of the beige mouse contain abnormally large lysosomes and show enhanced capping of concanavalin A. It has been suggested that these phenomena may be secondary to a defect in microtubule polymerization. We have examined the cytoskeleton of beige mouse cells by indirect immunofluorescence and fi...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1978
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110259/
https://www.ncbi.nlm.nih.gov/pubmed/363727
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collection PubMed
description Cells of the beige mouse contain abnormally large lysosomes and show enhanced capping of concanavalin A. It has been suggested that these phenomena may be secondary to a defect in microtubule polymerization. We have examined the cytoskeleton of beige mouse cells by indirect immunofluorescence and find the number and distribution of microtubules and actin cables to be indistinguishable from those of normal control cells.
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spelling pubmed-21102592008-05-01 Fibroblasts and macrophages of mice with the Chediak-Higashi-like syndrome have microtubules and actin cables J Cell Biol Articles Cells of the beige mouse contain abnormally large lysosomes and show enhanced capping of concanavalin A. It has been suggested that these phenomena may be secondary to a defect in microtubule polymerization. We have examined the cytoskeleton of beige mouse cells by indirect immunofluorescence and find the number and distribution of microtubules and actin cables to be indistinguishable from those of normal control cells. The Rockefeller University Press 1978-11-01 /pmc/articles/PMC2110259/ /pubmed/363727 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Fibroblasts and macrophages of mice with the Chediak-Higashi-like syndrome have microtubules and actin cables
title Fibroblasts and macrophages of mice with the Chediak-Higashi-like syndrome have microtubules and actin cables
title_full Fibroblasts and macrophages of mice with the Chediak-Higashi-like syndrome have microtubules and actin cables
title_fullStr Fibroblasts and macrophages of mice with the Chediak-Higashi-like syndrome have microtubules and actin cables
title_full_unstemmed Fibroblasts and macrophages of mice with the Chediak-Higashi-like syndrome have microtubules and actin cables
title_short Fibroblasts and macrophages of mice with the Chediak-Higashi-like syndrome have microtubules and actin cables
title_sort fibroblasts and macrophages of mice with the chediak-higashi-like syndrome have microtubules and actin cables
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110259/
https://www.ncbi.nlm.nih.gov/pubmed/363727

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