Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae

When the growth rate of the yeast Saccharomyces cerevisiae is limited with various nitrogen sources, the duration of the S phase is proportional to cell cycle length over a fourfold range of growth rates (C.J. Rivin and W. L. Fangman, 1980, J. Cell Biol. 85:96-107). Molecular parameters of the S pha...

Descripción completa

Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1980
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110590/
https://www.ncbi.nlm.nih.gov/pubmed/6767729
_version_ 1782139616566968320
collection PubMed
description When the growth rate of the yeast Saccharomyces cerevisiae is limited with various nitrogen sources, the duration of the S phase is proportional to cell cycle length over a fourfold range of growth rates (C.J. Rivin and W. L. Fangman, 1980, J. Cell Biol. 85:96-107). Molecular parameters of the S phases of these cells were examined by DNA fiber autoradiography. Changes in replication fork rate account completely for the changes in S-phase duration. No changes in origin-to- origin distances were detected. In addition, it was found that while most adjacent replication origins are activated within a few minutes of each other, new activations occur throughout the S phase.
format Text
id pubmed-2110590
institution National Center for Biotechnology Information
language English
publishDate 1980
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21105902008-05-01 Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae J Cell Biol Articles When the growth rate of the yeast Saccharomyces cerevisiae is limited with various nitrogen sources, the duration of the S phase is proportional to cell cycle length over a fourfold range of growth rates (C.J. Rivin and W. L. Fangman, 1980, J. Cell Biol. 85:96-107). Molecular parameters of the S phases of these cells were examined by DNA fiber autoradiography. Changes in replication fork rate account completely for the changes in S-phase duration. No changes in origin-to- origin distances were detected. In addition, it was found that while most adjacent replication origins are activated within a few minutes of each other, new activations occur throughout the S phase. The Rockefeller University Press 1980-04-01 /pmc/articles/PMC2110590/ /pubmed/6767729 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae
title Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae
title_full Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae
title_fullStr Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae
title_full_unstemmed Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae
title_short Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae
title_sort replication fork rate and origin activation during the s phase of saccharomyces cerevisiae
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110590/
https://www.ncbi.nlm.nih.gov/pubmed/6767729

Ejemplares similares