An endothelial cell-derived growth factor

Cell-free plasma-derived serum (PDS) is deficient in the platelet- derived growth factor and will not support the growth of 3T3 cells, fibroblasts, or smooth muscle cells. However, when PDS-containing medium is preincubated with endothelial cells, the medium becomes modified so that it will support...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1980
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110613/
https://www.ncbi.nlm.nih.gov/pubmed/7372716
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collection PubMed
description Cell-free plasma-derived serum (PDS) is deficient in the platelet- derived growth factor and will not support the growth of 3T3 cells, fibroblasts, or smooth muscle cells. However, when PDS-containing medium is preincubated with endothelial cells, the medium becomes modified so that it will support growth. The activity produced by the endothelial cells results from a polypeptide of 10,000 to 30,000 daltons which has several features that differ from those of the platelet-derived growth factor, including heat instability and lack of adsorption to CM Sephadex.
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spelling pubmed-21106132008-05-01 An endothelial cell-derived growth factor J Cell Biol Articles Cell-free plasma-derived serum (PDS) is deficient in the platelet- derived growth factor and will not support the growth of 3T3 cells, fibroblasts, or smooth muscle cells. However, when PDS-containing medium is preincubated with endothelial cells, the medium becomes modified so that it will support growth. The activity produced by the endothelial cells results from a polypeptide of 10,000 to 30,000 daltons which has several features that differ from those of the platelet-derived growth factor, including heat instability and lack of adsorption to CM Sephadex. The Rockefeller University Press 1980-05-01 /pmc/articles/PMC2110613/ /pubmed/7372716 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
An endothelial cell-derived growth factor
title An endothelial cell-derived growth factor
title_full An endothelial cell-derived growth factor
title_fullStr An endothelial cell-derived growth factor
title_full_unstemmed An endothelial cell-derived growth factor
title_short An endothelial cell-derived growth factor
title_sort endothelial cell-derived growth factor
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110613/
https://www.ncbi.nlm.nih.gov/pubmed/7372716

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