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Morphological changes of the adipose cell plasma membrane during lipolysis

Morphological changes of the plasma membrane in the white adipose cell associated with lipid mobilization were assessed qualitatively and quantitatively on freeze-fracture replicas of epididymal adipose tissue from fasted and from streptozotocin-diabetic rats. The number of plasma membrane invaginat...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110993/
https://www.ncbi.nlm.nih.gov/pubmed/137246
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collection PubMed
description Morphological changes of the plasma membrane in the white adipose cell associated with lipid mobilization were assessed qualitatively and quantitatively on freeze-fracture replicas of epididymal adipose tissue from fasted and from streptozotocin-diabetic rats. The number of plasma membrane invaginations and intramembranous particles were evaluated per square micrometer of membrane and per entire adipocyte. These two determinations show that the number per square micrometer (local concentration) of both structural features progressively increases with the duration of diabetes and fasting, while that at the same time their number per entire cell (total content) remains unchanged. These data thus show: (a) a reorganization of the adipose cell plasma membrane during lipolysis; and (b) that this reorganization can be detected only by determining the concentration and the total content of the structural features of the membrane involved.
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spelling pubmed-21109932008-05-01 Morphological changes of the adipose cell plasma membrane during lipolysis J Cell Biol Articles Morphological changes of the plasma membrane in the white adipose cell associated with lipid mobilization were assessed qualitatively and quantitatively on freeze-fracture replicas of epididymal adipose tissue from fasted and from streptozotocin-diabetic rats. The number of plasma membrane invaginations and intramembranous particles were evaluated per square micrometer of membrane and per entire adipocyte. These two determinations show that the number per square micrometer (local concentration) of both structural features progressively increases with the duration of diabetes and fasting, while that at the same time their number per entire cell (total content) remains unchanged. These data thus show: (a) a reorganization of the adipose cell plasma membrane during lipolysis; and (b) that this reorganization can be detected only by determining the concentration and the total content of the structural features of the membrane involved. The Rockefeller University Press 1977-01-01 /pmc/articles/PMC2110993/ /pubmed/137246 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Morphological changes of the adipose cell plasma membrane during lipolysis
title Morphological changes of the adipose cell plasma membrane during lipolysis
title_full Morphological changes of the adipose cell plasma membrane during lipolysis
title_fullStr Morphological changes of the adipose cell plasma membrane during lipolysis
title_full_unstemmed Morphological changes of the adipose cell plasma membrane during lipolysis
title_short Morphological changes of the adipose cell plasma membrane during lipolysis
title_sort morphological changes of the adipose cell plasma membrane during lipolysis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110993/
https://www.ncbi.nlm.nih.gov/pubmed/137246