Hormonal modulation of ovarian interstitial cells with particular reference to gap junctions

Thin-section and freeze-fracture studies on the rat ovarian interstitial cells revealed reductions in the size and the number of gap junctions after pituitary ablation. Small gap junctions, however, persist as long as 90 days after hypophysectomy even though regressive cytoplasmic changes are comple...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1979
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2111510/
https://www.ncbi.nlm.nih.gov/pubmed/479284
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collection PubMed
description Thin-section and freeze-fracture studies on the rat ovarian interstitial cells revealed reductions in the size and the number of gap junctions after pituitary ablation. Small gap junctions, however, persist as long as 90 days after hypophysectomy even though regressive cytoplasmic changes are completed 75 d earlier. Administration of exogenous human chorionic gonadotrophin (HCG) results in the restoration of the normal interstitial cell morphology which is accompanied by amplification of junctional membrane. Within 24 h of hormone application, gap junction growth is characterized by the appearance of formation plaques. These studies suggest that the effect of hormone on interstitial cell gap junctions is to modulate the junctional surface area.
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spelling pubmed-21115102008-05-01 Hormonal modulation of ovarian interstitial cells with particular reference to gap junctions J Cell Biol Articles Thin-section and freeze-fracture studies on the rat ovarian interstitial cells revealed reductions in the size and the number of gap junctions after pituitary ablation. Small gap junctions, however, persist as long as 90 days after hypophysectomy even though regressive cytoplasmic changes are completed 75 d earlier. Administration of exogenous human chorionic gonadotrophin (HCG) results in the restoration of the normal interstitial cell morphology which is accompanied by amplification of junctional membrane. Within 24 h of hormone application, gap junction growth is characterized by the appearance of formation plaques. These studies suggest that the effect of hormone on interstitial cell gap junctions is to modulate the junctional surface area. The Rockefeller University Press 1979-04-01 /pmc/articles/PMC2111510/ /pubmed/479284 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Hormonal modulation of ovarian interstitial cells with particular reference to gap junctions
title Hormonal modulation of ovarian interstitial cells with particular reference to gap junctions
title_full Hormonal modulation of ovarian interstitial cells with particular reference to gap junctions
title_fullStr Hormonal modulation of ovarian interstitial cells with particular reference to gap junctions
title_full_unstemmed Hormonal modulation of ovarian interstitial cells with particular reference to gap junctions
title_short Hormonal modulation of ovarian interstitial cells with particular reference to gap junctions
title_sort hormonal modulation of ovarian interstitial cells with particular reference to gap junctions
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2111510/
https://www.ncbi.nlm.nih.gov/pubmed/479284

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