Studies of the secretory process in the mammalian exocrine pancreas. I. The condensing vacuoles

Phosphatase cytochemistry was used to distinguish between the Golgi apparatus and GERL (considered as a specialized region of endoplasmic reticulum [ER] at the inner [trans] aspect of the Golgi stack) in pancreatic exocrine cells of guinea pig, rat, rabbit, and hamster. The trans element of the Golg...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2111565/
https://www.ncbi.nlm.nih.gov/pubmed/914894
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collection PubMed
description Phosphatase cytochemistry was used to distinguish between the Golgi apparatus and GERL (considered as a specialized region of endoplasmic reticulum [ER] at the inner [trans] aspect of the Golgi stack) in pancreatic exocrine cells of guinea pig, rat, rabbit, and hamster. The trans element of the Golgi stack exhibits thiamine pyrophosphatase (TPPase) but no acid phosphatase (AcPase) activity. In contrast, GERL shows AcPase but no TPPase activity. The nascent secretory granules, or condensing vacuoles, are expanded cisternal portions of GERL. Continuities of condensing vacuoles with rough ER are suggested, and it is proposed that some secretory components may have direct access to the condensing vacuoles from ER. Connections of Golgi apparatus with GERL were not seen.
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spelling pubmed-21115652008-05-01 Studies of the secretory process in the mammalian exocrine pancreas. I. The condensing vacuoles J Cell Biol Articles Phosphatase cytochemistry was used to distinguish between the Golgi apparatus and GERL (considered as a specialized region of endoplasmic reticulum [ER] at the inner [trans] aspect of the Golgi stack) in pancreatic exocrine cells of guinea pig, rat, rabbit, and hamster. The trans element of the Golgi stack exhibits thiamine pyrophosphatase (TPPase) but no acid phosphatase (AcPase) activity. In contrast, GERL shows AcPase but no TPPase activity. The nascent secretory granules, or condensing vacuoles, are expanded cisternal portions of GERL. Continuities of condensing vacuoles with rough ER are suggested, and it is proposed that some secretory components may have direct access to the condensing vacuoles from ER. Connections of Golgi apparatus with GERL were not seen. The Rockefeller University Press 1977-10-01 /pmc/articles/PMC2111565/ /pubmed/914894 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Studies of the secretory process in the mammalian exocrine pancreas. I. The condensing vacuoles
title Studies of the secretory process in the mammalian exocrine pancreas. I. The condensing vacuoles
title_full Studies of the secretory process in the mammalian exocrine pancreas. I. The condensing vacuoles
title_fullStr Studies of the secretory process in the mammalian exocrine pancreas. I. The condensing vacuoles
title_full_unstemmed Studies of the secretory process in the mammalian exocrine pancreas. I. The condensing vacuoles
title_short Studies of the secretory process in the mammalian exocrine pancreas. I. The condensing vacuoles
title_sort studies of the secretory process in the mammalian exocrine pancreas. i. the condensing vacuoles
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2111565/
https://www.ncbi.nlm.nih.gov/pubmed/914894

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