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Recognition and receptor-mediated uptake of phosphorylated high mannose- type oligosaccharides by cultured human fibroblasts
The intracellular transport of newly synthesized lysosomal hydrolases to lysosomes requires the presence of one or more phosphorylated high mannose-type oligosaccharides per enzyme. A receptor that mediates mannose-6-PO4-specific uptake of lysosomal enzymes is expressed on the surface of fibroblasts...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1983
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2112397/ https://www.ncbi.nlm.nih.gov/pubmed/6300141 |