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Growth regulatory effects of cyclic AMP and polyamine depletion are dissociable in cultured mouse lymphoma cells
Treatment of mouse lymphoma S49 cells with D,L-alpha- difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, depleted cellular polyamine levels and stopped cell growth. The cells were arrested predominantly in G1. Thus, polyamine depletion may lead to a regulatory growth arrest in...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1983
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2112398/ https://www.ncbi.nlm.nih.gov/pubmed/6300139 |