Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis

Indirect immunofluorescence, immunoelectron microscopy, and digestion by protease were used to study intracellular transport of the G protein of vesicular stomatitis virus in mitotic and interphase cells. Quantitation showed that the appearance of G protein on the surface of mitotic cells was inhibi...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1983
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Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2112686/
https://www.ncbi.nlm.nih.gov/pubmed/6355124
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collection PubMed
description Indirect immunofluorescence, immunoelectron microscopy, and digestion by protease were used to study intracellular transport of the G protein of vesicular stomatitis virus in mitotic and interphase cells. Quantitation showed that the appearance of G protein on the surface of mitotic cells was inhibited at least 10-fold when compared with that on interphase cells, even though similar amounts of viral protein were being synthesized. This dramatic inhibition, taken together with the simultaneous inhibition of endocytosis (Berlin, R. D., and J. M. Oliver, 1980, J. Cell Biol. 85: 660-671), points to a general cessation of membrane traffic in the mitotic cell.
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spelling pubmed-21126862008-05-01 Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis J Cell Biol Articles Indirect immunofluorescence, immunoelectron microscopy, and digestion by protease were used to study intracellular transport of the G protein of vesicular stomatitis virus in mitotic and interphase cells. Quantitation showed that the appearance of G protein on the surface of mitotic cells was inhibited at least 10-fold when compared with that on interphase cells, even though similar amounts of viral protein were being synthesized. This dramatic inhibition, taken together with the simultaneous inhibition of endocytosis (Berlin, R. D., and J. M. Oliver, 1980, J. Cell Biol. 85: 660-671), points to a general cessation of membrane traffic in the mitotic cell. The Rockefeller University Press 1983-11-01 /pmc/articles/PMC2112686/ /pubmed/6355124 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis
title Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis
title_full Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis
title_fullStr Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis
title_full_unstemmed Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis
title_short Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis
title_sort newly synthesized g protein of vesicular stomatitis virus is not transported to the cell surface during mitosis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2112686/
https://www.ncbi.nlm.nih.gov/pubmed/6355124

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