Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation

Neutrophils isolated from the blood were compared to those from inflammatory exudates in the peritoneal cavity of guinea pigs. Inflammatory neutrophils were shown to have 10-fold more glycogen than blood neutrophils. This was also reflected in the morphology of these cells. The large accumulations o...

Descripción completa

Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1982
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2112917/
https://www.ncbi.nlm.nih.gov/pubmed/7153252
_version_ 1782140067039412224
collection PubMed
description Neutrophils isolated from the blood were compared to those from inflammatory exudates in the peritoneal cavity of guinea pigs. Inflammatory neutrophils were shown to have 10-fold more glycogen than blood neutrophils. This was also reflected in the morphology of these cells. The large accumulations of glycogen in inflammatory neutrophils exists in ordered arrays of beta-granules. Other morphological changes including accumulations of lipid droplets and a decrease in the number of lysosomal granules also accompany the change from blood neutrophils to inflammatory neutrophils. These results show that there are major metabolic differences in the two types of neutrophils.
format Text
id pubmed-2112917
institution National Center for Biotechnology Information
language English
publishDate 1982
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21129172008-05-01 Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation J Cell Biol Articles Neutrophils isolated from the blood were compared to those from inflammatory exudates in the peritoneal cavity of guinea pigs. Inflammatory neutrophils were shown to have 10-fold more glycogen than blood neutrophils. This was also reflected in the morphology of these cells. The large accumulations of glycogen in inflammatory neutrophils exists in ordered arrays of beta-granules. Other morphological changes including accumulations of lipid droplets and a decrease in the number of lysosomal granules also accompany the change from blood neutrophils to inflammatory neutrophils. These results show that there are major metabolic differences in the two types of neutrophils. The Rockefeller University Press 1982-12-01 /pmc/articles/PMC2112917/ /pubmed/7153252 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation
title Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation
title_full Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation
title_fullStr Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation
title_full_unstemmed Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation
title_short Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation
title_sort glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2112917/
https://www.ncbi.nlm.nih.gov/pubmed/7153252

Ejemplares similares