Mapping nucleolar proteins with monoclonal antibodies

Using monoclonal antibodies as probes, we have characterized three antigens with respect to localization in the nucleolus, molecular weight and solubility. Two proteins, of 110,000 and 94,000 apparent molecular weight, were found associated with the ribonucleoprotein fibers. A third protein, with a...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1984
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113565/
https://www.ncbi.nlm.nih.gov/pubmed/6209284
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description Using monoclonal antibodies as probes, we have characterized three antigens with respect to localization in the nucleolus, molecular weight and solubility. Two proteins, of 110,000 and 94,000 apparent molecular weight, were found associated with the ribonucleoprotein fibers. A third protein, with a molecular weight of 40,000, was accumulated at the nucleolar periphery, was present in the nucleoplasm, and may be involved in pre-ribosome maturation and transport.
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spelling pubmed-21135652008-05-01 Mapping nucleolar proteins with monoclonal antibodies J Cell Biol Articles Using monoclonal antibodies as probes, we have characterized three antigens with respect to localization in the nucleolus, molecular weight and solubility. Two proteins, of 110,000 and 94,000 apparent molecular weight, were found associated with the ribonucleoprotein fibers. A third protein, with a molecular weight of 40,000, was accumulated at the nucleolar periphery, was present in the nucleoplasm, and may be involved in pre-ribosome maturation and transport. The Rockefeller University Press 1984-12-01 /pmc/articles/PMC2113565/ /pubmed/6209284 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Mapping nucleolar proteins with monoclonal antibodies
title Mapping nucleolar proteins with monoclonal antibodies
title_full Mapping nucleolar proteins with monoclonal antibodies
title_fullStr Mapping nucleolar proteins with monoclonal antibodies
title_full_unstemmed Mapping nucleolar proteins with monoclonal antibodies
title_short Mapping nucleolar proteins with monoclonal antibodies
title_sort mapping nucleolar proteins with monoclonal antibodies
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113565/
https://www.ncbi.nlm.nih.gov/pubmed/6209284

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