Cargando…

Glucocorticoids increase amylase mRNA levels, secretory organelles, and secretion in pancreatic acinar AR42J cells

Previous studies have suggested a role for glucocorticoids in the differentiation of the acinar pancreas. We have now used the rat tumor cell line AR42J, derived from the acinar pancreas, to directly study this effect of glucocorticoids in vitro. The steroid hormones dexamethasone, corticosterone, a...

Descripción completa

Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1985
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113760/ https://www.ncbi.nlm.nih.gov/pubmed/2579957

Ejemplares similares

Glucocorticoids have opposite effects on ornithine decarboxylase and cell growth in pancreatic acinar AR42J cells.
por: Logsdon, C. D., et al.
Publicado: (1992)

Rab3D regulates amylase levels, not agonist-induced amylase release, in AR42J cells
por: Limi, Saima, et al.
Publicado: (2012)

Pim-3 alleviates lipopolysaccharide-stimulated AR42J pancreatic acinar cell injury via improving the inflammatory microenvironment
por: Jian, Jie, et al.
Publicado: (2019)

Lycopene Inhibits Oxidative Stress-Mediated Inflammatory Responses in Ethanol/Palmitoleic Acid-Stimulated Pancreatic Acinar AR42J Cells
por: Lee, Jaeeun, et al.
Publicado: (2021)

Pitfalls in AR42J-model of cerulein-induced acute pancreatitis
por: Hollenbach, Marcus, et al.
Publicado: (2021)

Da Cheng Qi Decoction Alleviates Cerulein-Stimulated AR42J Pancreatic Acinar Cell Injury via the JAK2/STAT3 Signaling Pathway
por: Zhou, Zehua, et al.
Publicado: (2021)

Protective effects of baicalin on caerulein-induced AR42J pancreatic acinar cells by attenuating oxidative stress through miR-136-5p downregulation
por: Zhao, Zhu-fen, et al.
Publicado: (2021)

Inhibitory effect of high leucine concentration on α-amylase secretion by pancreatic acinar cells: possible key factor of proteasome
por: Guo, Long, et al.
Publicado: (2018)

Intracellular transport and storage of secretory proteins in relation to cytodifferentiation in neoplastic pancreatic acinar cells
Publicado: (1983)

Using CRISPR/Cas9 to Knock out Amylase in Acinar Cells Decreases Pancreatitis-Induced Autophagy
por: Yasunaga, Kohei, et al.
Publicado: (2018)

Pancreatic Ductal Bicarbonate Secretion: Challenge of the Acinar Acid Load
por: Hegyi, Péter, et al.
Publicado: (2011)

Biochemical analysis of secretory proteins synthesized by normal rat pancreas and by pancreatic acinar tumor cells
Publicado: (1982)

Comparison of secretory protein profiles in developing rat pancreatic rudiments and rat acinar tumor cells
Publicado: (1982)

On atmospheric $^{39}Ar$ and $^{42}Ar$ abundance
por: Cennini, P, et al.
Publicado: (1995)

Enhanced proliferation of pancreatic acinar cells in MRL/MpJ mice is driven by severe acinar injury but independent of inflammation
por: Bombardo, Marta, et al.
Publicado: (2018)

RADIOAUTOGRAPHIC ANALYSIS OF THE SECRETORY PROCESS IN THE PAROTID ACINAR CELL OF THE RABBIT
por: Castle, J. David, et al.
Publicado: (1972)

Protective Effects of Oleic Acid Against Palmitic Acid-Induced Apoptosis in Pancreatic AR42J Cells and Its Mechanisms
por: Ahn, Joung Hoon, et al.
Publicado: (2013)

Formula Compatibility Identification of Dachengqi Decoction Based on the Effects of Absorbed Components in Cerulein-Injured Pancreatic AR42J Cells
por: Zhang, Yumei, et al.
Publicado: (2016)

Extracellular Histones Activate Plasma Membrane Toll-Like Receptor 9 to Trigger Calcium Oscillations in Rat Pancreatic Acinar Tumor Cell AR4-2J
por: Guo, Hai Yan, et al.
Publicado: (2018)

Proteomics of Secretory and Endocytic Organelles in Giardia lamblia
por: Wampfler, Petra B., et al.
Publicado: (2014)

Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors
por: Koblas, Tomas, et al.
Publicado: (2016)

Pancreatic Acinar Cell Carcinoma
por: Béchade, Dominique, et al.
Publicado: (2016)

Phenylalanine regulates initiation of digestive enzyme mRNA translation in pancreatic acinar cells and tissue segments in dairy calves
por: Guo, Long, et al.
Publicado: (2018)

Regulation of AR mRNA translation in response to acute AR pathway inhibition
por: Somasekharan, Syam Prakash, et al.
Publicado: (2021)

Glucocorticoid receptor regulates expression of microRNA-22 and downstream signaling pathway in apoptosis of pancreatic acinar cells
por: Fu, Qiang, et al.
Publicado: (2018)

Mitogenic and functional responses by nicotine and hydrogen peroxide in AR42J cells: a comparative study
por: Walker, Azida, et al.
Publicado: (2008)

IP3 Receptor Type 2 Deficiency Is Associated with a Secretory Defect in the Pancreatic Acinar Cell and an Accumulation of Zymogen Granules
por: Orabi, Abrahim I., et al.
Publicado: (2012)

Tip-end fusion of a rod-shaped secretory organelle
por: Naß, Johannes, et al.
Publicado: (2022)

Peroxisome function relies on organelle-associated mRNA translation
por: Dahan, Noa, et al.
Publicado: (2022)

Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion
por: Hou, Yanan, et al.
Publicado: (2015)

Regulated Exocytosis in the Pancreatic Acinar Cell
por: Jamieson, J.D., et al.
Publicado: (1997)

Discussion: Pancreatic Acinar Cell Pathophysiology
por: Gorelick, Fred S.
Publicado: (1992)

SULFATE METABOLISM IN PANCREATIC ACINAR CELLS
por: Berg, Norton B., et al.
Publicado: (1971)

TGF-β1 promotes acinar to ductal metaplasia of human pancreatic acinar cells
por: Liu, Jun, et al.
Publicado: (2016)

DYNAMIC CHANGES IN THE ULTRASTRUCTURE OF THE ACINAR CELL OF THE RAT PAROTID GLAND DURING THE SECRETORY CYCLE
por: Amsterdam, Avraham, et al.
Publicado: (1969)

AR mRNA stability is increased with AR-antagonist resistance via 3′UTR variants
por: Dart, D A, et al.
Publicado: (2019)

Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs
por: Liou, Geou-Yarh, et al.
Publicado: (2013)

Early to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar Cells
por: Messenger, Scott W., et al.
Publicado: (2015)

PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia
por: Dey, Parama, et al.
Publicado: (2014)

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication
por: Hsu, Nai-Yun, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_55lcf06quqsk0dtlglvb5rgmgu