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Chymotrypsin substrate analogues inhibit endocytosis of insulin and insulin receptors in adipocytes
To explore the possible role of proteolytic step(s) in receptor- mediated endocytosis of insulin, the effects of inhibitors of various classes of proteases on the internalization process were studied in isolated rat adipocytes. Intracellular accumulation of receptor-bound 125I-insulin at 37 degrees...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1986
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114384/ https://www.ncbi.nlm.nih.gov/pubmed/2877995 |