A lithium-sensitive regulator of sperm flagellar oscillation is activated by cAMP-dependent phosphorylation

Specific effects of both in vivo activation and in vitro activation by cAMP-dependent phosphorylation on bending wave parameters of demembranated, reactivated, tunicate (Ciona intestinalis) and sea urchin (Lytechinus pictus) sperm flagella can be reversed by exposure to protein phosphatase. The effe...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1987
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114665/
https://www.ncbi.nlm.nih.gov/pubmed/2822725
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collection PubMed
description Specific effects of both in vivo activation and in vitro activation by cAMP-dependent phosphorylation on bending wave parameters of demembranated, reactivated, tunicate (Ciona intestinalis) and sea urchin (Lytechinus pictus) sperm flagella can be reversed by exposure to protein phosphatase. The effects of protein phosphatase incubation can be imitated by inclusion of LiCl in the reactivation solutions. The primary effect of cAMP-dependent phosphorylation appears to be activation of a regulatory mechanism controlling flagellar oscillation, rather than activation of the active sliding mechanism. Lithium appears to act on the same regulatory mechanism.
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spelling pubmed-21146652008-05-01 A lithium-sensitive regulator of sperm flagellar oscillation is activated by cAMP-dependent phosphorylation J Cell Biol Articles Specific effects of both in vivo activation and in vitro activation by cAMP-dependent phosphorylation on bending wave parameters of demembranated, reactivated, tunicate (Ciona intestinalis) and sea urchin (Lytechinus pictus) sperm flagella can be reversed by exposure to protein phosphatase. The effects of protein phosphatase incubation can be imitated by inclusion of LiCl in the reactivation solutions. The primary effect of cAMP-dependent phosphorylation appears to be activation of a regulatory mechanism controlling flagellar oscillation, rather than activation of the active sliding mechanism. Lithium appears to act on the same regulatory mechanism. The Rockefeller University Press 1987-10-01 /pmc/articles/PMC2114665/ /pubmed/2822725 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
A lithium-sensitive regulator of sperm flagellar oscillation is activated by cAMP-dependent phosphorylation
title A lithium-sensitive regulator of sperm flagellar oscillation is activated by cAMP-dependent phosphorylation
title_full A lithium-sensitive regulator of sperm flagellar oscillation is activated by cAMP-dependent phosphorylation
title_fullStr A lithium-sensitive regulator of sperm flagellar oscillation is activated by cAMP-dependent phosphorylation
title_full_unstemmed A lithium-sensitive regulator of sperm flagellar oscillation is activated by cAMP-dependent phosphorylation
title_short A lithium-sensitive regulator of sperm flagellar oscillation is activated by cAMP-dependent phosphorylation
title_sort lithium-sensitive regulator of sperm flagellar oscillation is activated by camp-dependent phosphorylation
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114665/
https://www.ncbi.nlm.nih.gov/pubmed/2822725

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