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Anti-peptide antibodies detect steps in a protein conformational change: low-pH activation of the influenza virus hemagglutinin
At low pH, the hemagglutinin (HA) of influenza virus undergoes an irreversible conformational change that potentiates its essential membrane fusion function. We have probed the details of this conformational change using a panel of 14 anti-HA-peptide antibodies. Whereas some antibodies reacted equal...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1987
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114698/ https://www.ncbi.nlm.nih.gov/pubmed/2447101 |