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Early hypomethylation of 2'-O-ribose moieties in hepatocyte cytoplasmic ribosomal RNA underlies the protein synthetic defect produced by CCl4
Carbon tetrachloride (CCl4) treatment of rats produces an early defect in methylation of hepatocyte ribosomal RNA, which occurs concurrently with a defect in the protein synthetic capacity of isolated ribosomes. The CCl4-induced methylation defect is specific for the 2'-O-ribose position, and a...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1987
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114784/ https://www.ncbi.nlm.nih.gov/pubmed/3114267 |