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A tripartite structure of the signals that determine protein insertion into the endoplasmic reticulum membrane
Multilineage colony stimulating factor is a secretory protein with a cleavable signal sequence that is unusually long and hydrophobic. Using molecular cloning techniques we exchanged sequences NH2- or COOH- terminally flanking the hydrophobic signal sequence. Such modified fusion proteins still inse...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1989
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2115504/ https://www.ncbi.nlm.nih.gov/pubmed/2784443 |