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Drosophila laminin: sequence of B2 subunit and expression of all three subunits during embryogenesis
In a previous study, we described the cloning of the genes encoding the three subunits of Drosophila laminin, a substrate adhesion molecule, and the cDNA sequence of the B1 subunit (Montell and Goodman, 1988). This analysis revealed the similarity of Drosophila laminin with the mouse and human compl...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1989
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2115843/ https://www.ncbi.nlm.nih.gov/pubmed/2808533 |
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collection | PubMed |
description | In a previous study, we described the cloning of the genes encoding the three subunits of Drosophila laminin, a substrate adhesion molecule, and the cDNA sequence of the B1 subunit (Montell and Goodman, 1988). This analysis revealed the similarity of Drosophila laminin with the mouse and human complexes in subunit composition, domain structure, and amino acid sequence. In this paper, we report the deduced amino acid sequence of the B2 subunit. We then describe the expression and tissue distribution of the three subunits of laminin during Drosophila embryogenesis using both in situ hybridization and immunolocalization techniques, with particular emphasis on its expression in and around the developing nervous system. |
format | Text |
id | pubmed-2115843 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1989 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21158432008-05-01 Drosophila laminin: sequence of B2 subunit and expression of all three subunits during embryogenesis J Cell Biol Articles In a previous study, we described the cloning of the genes encoding the three subunits of Drosophila laminin, a substrate adhesion molecule, and the cDNA sequence of the B1 subunit (Montell and Goodman, 1988). This analysis revealed the similarity of Drosophila laminin with the mouse and human complexes in subunit composition, domain structure, and amino acid sequence. In this paper, we report the deduced amino acid sequence of the B2 subunit. We then describe the expression and tissue distribution of the three subunits of laminin during Drosophila embryogenesis using both in situ hybridization and immunolocalization techniques, with particular emphasis on its expression in and around the developing nervous system. The Rockefeller University Press 1989-11-01 /pmc/articles/PMC2115843/ /pubmed/2808533 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Drosophila laminin: sequence of B2 subunit and expression of all three subunits during embryogenesis |
title | Drosophila laminin: sequence of B2 subunit and expression of all three subunits during embryogenesis |
title_full | Drosophila laminin: sequence of B2 subunit and expression of all three subunits during embryogenesis |
title_fullStr | Drosophila laminin: sequence of B2 subunit and expression of all three subunits during embryogenesis |
title_full_unstemmed | Drosophila laminin: sequence of B2 subunit and expression of all three subunits during embryogenesis |
title_short | Drosophila laminin: sequence of B2 subunit and expression of all three subunits during embryogenesis |
title_sort | drosophila laminin: sequence of b2 subunit and expression of all three subunits during embryogenesis |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2115843/ https://www.ncbi.nlm.nih.gov/pubmed/2808533 |