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Echistatin is a potent inhibitor of bone resorption in culture
The venom protein, s-echistatin, originally derived from the saw-scaled viper Echis carinatus, was found to be a potent inhibitor of bone resorption by isolated osteoclasts. This Arg24-Gly25-Asp26-(RGD)- containing protein inhibited the excavation of bone slices by rat osteoclasts (IC50 = 0.1 nM). I...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2116239/ https://www.ncbi.nlm.nih.gov/pubmed/2211834 |