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Invariant chain trimers are sequestered in the rough endoplasmic reticulum in the absence of association with HLA class II antigens
HLA class II antigens are heterodimeric cell surface glycoproteins that interact with antigenic peptides to form complexes recognizable by CD4- positive T cells. During their biosynthesis, class II antigens are retained in a post-Golgi compartment in association with the invariant chain, which disso...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2116304/ https://www.ncbi.nlm.nih.gov/pubmed/2391366 |