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Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti–HIV-1 activity

Apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G), a cytidine deaminase, is a recently recognized innate intracellular protein with lethal activity against human immunodeficiency virus (HIV). Packaged into progeny virions, APOBEC3G enzymatic activity leads to HIV DNA degr...

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Detalles Bibliográficos
Autores principales: Peng, Gang, Lei, Ke Jian, Jin, Wenwen, Greenwell-Wild, Teresa, Wahl, Sharon M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118075/
https://www.ncbi.nlm.nih.gov/pubmed/16418394
http://dx.doi.org/10.1084/jem.20051512