Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock

Activation of the mitogen-activated protein kinase (MAPK) cascade after Toll-like receptor stimulation enables innate immune cells to rapidly activate cytokine gene expression. A balanced response to signals of infectious danger requires that cellular activation is transient. Here, we identify the M...

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Detalles Bibliográficos
Autores principales: Hammer, Michael, Mages, Jörg, Dietrich, Harald, Servatius, Angela, Howells, Norma, Cato, Andrew C.B., Lang, Roland
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118077/
https://www.ncbi.nlm.nih.gov/pubmed/16380512
http://dx.doi.org/10.1084/jem.20051753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118077/
https://www.ncbi.nlm.nih.gov/pubmed/16380512
http://dx.doi.org/10.1084/jem.20051753

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