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TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque
Acute coronary syndromes (ACS) are precipitated by a rupture of the atherosclerotic plaque, often at the site of T cell and macrophage infiltration. Here, we show that plaque-infiltrating CD4 T cells effectively kill vascular smooth muscle cells (VSMC). VSMCs sensitive to T cell–mediated killing exp...
Autores principales: | Sato, Kayoko, Niessner, Alexander, Kopecky, Stephen L., Frye, Robert L., Goronzy, Jörg J., Weyand, Cornelia M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118078/ https://www.ncbi.nlm.nih.gov/pubmed/16418392 http://dx.doi.org/10.1084/jem.20051062 |
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