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Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression

Glucocorticoids are the most effective antiinflammatory agents for the treatment of chronic inflammatory diseases even though some diseases, such as chronic obstructive pulmonary disease (COPD), are relatively glucocorticoid insensitive. However, the molecular mechanism of this glucocorticoid insens...

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Detalles Bibliográficos
Autores principales:	Ito, Kazuhiro, Yamamura, Satoshi, Essilfie-Quaye, Sarah, Cosio, Borja, Ito, Misako, Barnes, Peter J., Adcock, Ian M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118081/ https://www.ncbi.nlm.nih.gov/pubmed/16380507 http://dx.doi.org/10.1084/jem.20050466

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