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B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion
B-1 B cells produce circulating natural antibodies that provide “innate-like” protection against bacterial and viral pathogens. They also provide adaptive responses to blood and air-borne pathogens. B lymphocyte–induced maturation protein 1 (Blimp-1) is a transcriptional repressor that is required f...
Autores principales: | Savitsky, David, Calame, Kathryn |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118107/ https://www.ncbi.nlm.nih.gov/pubmed/16954370 http://dx.doi.org/10.1084/jem.20060411 |
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