BAFF controls B cell metabolic fitness through a PKCβ- and Akt-dependent mechanism

B cell life depends critically on the cytokine B cell–activating factor of the tumor necrosis factor family (BAFF). Lack of BAFF signaling leads to B cell death and immunodeficiency. Excessive BAFF signaling promotes lupus-like autoimmunity. Despite the great importance of BAFF to B cell biology, it...

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Detalles Bibliográficos
Autores principales: Patke, Alina, Mecklenbräuker, Ingrid, Erdjument-Bromage, Hediye, Tempst, Paul, Tarakhovsky, Alexander
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118121/
https://www.ncbi.nlm.nih.gov/pubmed/17060474
http://dx.doi.org/10.1084/jem.20060990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118121/
https://www.ncbi.nlm.nih.gov/pubmed/17060474
http://dx.doi.org/10.1084/jem.20060990

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