A role for Dicer in immune regulation

Micro RNAs (miRNAs) regulate gene expression at the posttranscriptional level. Here we show that regulatory T (T reg) cells have a miRNA profile distinct from conventional CD4 T cells. A partial T reg cell–like miRNA profile is conferred by the enforced expression of Foxp3 and, surprisingly, by the...

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Detalles Bibliográficos
Autores principales: Cobb, Bradley S., Hertweck, Arnulf, Smith, James, O'Connor, Eric, Graf, Daniel, Cook, Terence, Smale, Stephen T., Sakaguchi, Shimon, Livesey, Frederick J., Fisher, Amanda G., Merkenschlager, Matthias
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118134/
https://www.ncbi.nlm.nih.gov/pubmed/17060477
http://dx.doi.org/10.1084/jem.20061692

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