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Plasma cell S1P(1) expression determines secondary lymphoid organ retention versus bone marrow tropism
After induction in secondary lymphoid organs, a subset of antibody-secreting cells (ASCs) homes to the bone marrow (BM) and contributes to long-term antibody production. The factors determining secondary lymphoid organ residence versus BM tropism have been unclear. Here we demonstrate that in mice t...
Autores principales: | Kabashima, Kenji, Haynes, Nicole M., Xu, Ying, Nutt, Stephen L., Allende, Maria L., Proia, Richard L., Cyster, Jason G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118149/ https://www.ncbi.nlm.nih.gov/pubmed/17101733 http://dx.doi.org/10.1084/jem.20061289 |
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