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Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

In autoimmune arthritis, traditionally classified as a T helper (Th) type 1 disease, the activation of T cells results in bone destruction mediated by osteoclasts, but how T cells enhance osteoclastogenesis despite the anti-osteoclastogenic effect of interferon (IFN)-γ remains to be elucidated. Here...

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Detalles Bibliográficos
Autores principales:	Sato, Kojiro, Suematsu, Ayako, Okamoto, Kazuo, Yamaguchi, Akira, Morishita, Yasuyuki, Kadono, Yuho, Tanaka, Sakae, Kodama, Tatsuhiko, Akira, Shizuo, Iwakura, Yoichiro, Cua, Daniel J., Takayanagi, Hiroshi
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118166/ https://www.ncbi.nlm.nih.gov/pubmed/17088434 http://dx.doi.org/10.1084/jem.20061775

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