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A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2

Commensalism is critical to a healthy Th1/Th2 cell balance. Polysaccharide A (PSA), which is produced by the intestinal commensal Bacteroides fragilis, activates CD4(+) T cells, resulting in a Th1 response correcting the Th2 cell skew of germ-free mice. We identify Toll-like receptors as crucial to...

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Detalles Bibliográficos
Autores principales:	Wang, Qun, McLoughlin, Rachel M., Cobb, Brian A., Charrel-Dennis, Marie, Zaleski, Kathleen J., Golenbock, Douglas, Tzianabos, Arthur O., Kasper, Dennis L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118167/ https://www.ncbi.nlm.nih.gov/pubmed/17178920 http://dx.doi.org/10.1084/jem.20062008

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