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APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection

HIV-1 infects immature dendritic cells (iDCs), but infection is inefficient compared with activated CD4(+) T cells and only involves a small subset of iDCs. We analyzed whether this could be attributed to specific cellular restrictions during the viral life cycle. To study env-independent restrictio...

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Detalles Bibliográficos
Autores principales: Pion, Marjorie, Granelli-Piperno, Angela, Mangeat, Bastien, Stalder, Romaine, Correa, Rafael, Steinman, Ralph M., Piguet, Vincent
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118170/
https://www.ncbi.nlm.nih.gov/pubmed/17145955
http://dx.doi.org/10.1084/jem.20061519