Cargando…
Acquisition of direct antiviral effector functions by CMV-specific CD4(+) T lymphocytes with cellular maturation
The role of CD4(+) T cells in the control of persistent viral infections beyond the provision of cognate help remains unclear. We used polychromatic flow cytometry to evaluate the production of the cytokines interferon (IFN)-γ, tumor necrosis factor (TNF)-α, and interleukin (IL)-2, the chemokine mac...
Autores principales: | Casazza, Joseph P., Betts, Michael R., Price, David A., Precopio, Melissa L., Ruff, Laura E., Brenchley, Jason M., Hill, Brenna J., Roederer, Mario, Douek, Daniel C., Koup, Richard A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118179/ https://www.ncbi.nlm.nih.gov/pubmed/17158960 http://dx.doi.org/10.1084/jem.20052246 |
Ejemplares similares
-
Autocrine Production of β-Chemokines Protects CMV-Specific CD4(+) T Cells from HIV Infection
por: Casazza, Joseph P., et al.
Publicado: (2009) -
PD-1 is a regulator of virus-specific CD8(+) T cell survival in HIV infection
por: Petrovas, Constantinos, et al.
Publicado: (2006) -
Avidity for antigen shapes clonal dominance in CD8(+) T cell populations specific for persistent DNA viruses
por: Price, David A., et al.
Publicado: (2005) -
Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses
por: Precopio, Melissa L., et al.
Publicado: (2007) -
Increased differentiation associates with decreased polyfunctionality for HIV but not CMV-specific CD8+ T cell responses
por: Riou, C, et al.
Publicado: (2012)