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Essential role of the T cell–specific adapter protein in the activation of LCK in peripheral T cells

T cell–specific adapter protein (TSAd) is a SRC-homology-2 (SH2) domain–containing intracellular signaling molecule that is required for T cell antigen receptor (TCR)–induced cytokine synthesis in T cells. How TSAd functions in TCR signal transduction is not clear. Previous work has suggested a nucl...

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Detalles Bibliográficos
Autores principales:	Marti, Francesc, Garcia, Gonzalo G., Lapinski, Philip E., MacGregor, Jennifer N., King, Philip D.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118198/ https://www.ncbi.nlm.nih.gov/pubmed/16446380 http://dx.doi.org/10.1084/jem.20051637

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