Cargando…

ATM regulates ATR chromatin loading in response to DNA double-strand breaks

DNA double-strand breaks (DSBs) are among the most deleterious lesions that can challenge genomic integrity. Concomitant to the repair of the breaks, a rapid signaling cascade must be coordinated at the lesion site that leads to the activation of cell cycle checkpoints and/or apoptosis. In this cont...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cuadrado, Myriam, Martinez-Pastor, Barbara, Murga, Matilde, Toledo, Luis I., Gutierrez-Martinez, Paula, Lopez, Eva, Fernandez-Capetillo, Oscar
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118201/ https://www.ncbi.nlm.nih.gov/pubmed/16461339 http://dx.doi.org/10.1084/jem.20051923

Ejemplares similares

"ATR activation in response to ionizing radiation: still ATM territory"
por: Cuadrado, Myriam, et al.
Publicado: (2006)

Immature Thymocytes Undergoing Receptor Rearrangements Are Resistant to an Atm-Dependent Death Pathway Activated in Mature T Cells by Double-Stranded DNA Breaks
por: Bhandoola, Avinash, et al.
Publicado: (2000)

Dynamic Dependence on ATR and ATM for Double-Strand Break Repair in Human Embryonic Stem Cells and Neural Descendants
por: Adams, Bret R., et al.
Publicado: (2010)

Selective Inhibition of ATM-dependent Double-strand Break Repair and Checkpoint Control Synergistically Enhances the Efficacy of ATR Inhibitors
por: Turchick, Audrey, et al.
Publicado: (2023)

Global chromatin compaction limits the strength of the DNA damage response
por: Murga, Matilde, et al.
Publicado: (2007)

DNA Double-Strand Breaks: Prior to but not Sufficient in Targeting Hypermutation
por: Bross, Linda, et al.
Publicado: (2002)

ATM controls meiotic double-strand break formation
por: Lange, Julian, et al.
Publicado: (2011)

ATM’s Role in the Repair of DNA Double-Strand Breaks
por: Shibata, Atsushi, et al.
Publicado: (2021)

Limited Role of Murine ATM in Oncogene-Induced Senescence and p53-Dependent Tumor Suppression
por: Efeyan, Alejo, et al.
Publicado: (2009)

The Caenorhabditis elegans Werner Syndrome Protein Functions Upstream of ATR and ATM in Response to DNA Replication Inhibition and Double-Strand DNA Breaks
por: Lee, Se-Jin, et al.
Publicado: (2010)

Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
por: Kruhlak, Michael J., et al.
Publicado: (2006)

ATM specifically mediates repair of double-strand breaks with blocked DNA ends
por: Álvarez-Quilón, Alejandro, et al.
Publicado: (2014)

ATM Alters the Otherwise Robust Chromatin Mobility at Sites of DNA Double-Strand Breaks (DSBs) in Human Cells
por: Becker, Annabelle, et al.
Publicado: (2014)

ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase
por: McNees, Carolyn J., et al.
Publicado: (2010)

Phosphorylation of Histone H2B at DNA Double-Strand Breaks
por: Fernandez-Capetillo, Oscar, et al.
Publicado: (2004)

Budding Yeast ATM/ATR Control Meiotic Double-Strand Break (DSB) Levels by Down-Regulating Rec114, an Essential Component of the DSB-machinery
por: Carballo, Jesús A., et al.
Publicado: (2013)

Yeast ATM and ATR kinases use different mechanisms to spread histone H2A phosphorylation around a DNA double-strand break
por: Li, Kevin, et al.
Publicado: (2020)

The Chromatin Response to Double-Strand DNA Breaks and Their Repair
por: Aleksandrov, Radoslav, et al.
Publicado: (2020)

Double-strand break toxicity is chromatin context independent
por: Friskes, Anoek, et al.
Publicado: (2022)

The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination
por: Chahwan, Richard, et al.
Publicado: (2012)

NBN Phosphorylation regulates the accumulation of MRN and ATM at sites of DNA Double-Strand Breaks
por: Wen, Jie, et al.
Publicado: (2012)

Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks
por: Caron, Pierre, et al.
Publicado: (2015)

Coping with DNA Double-Strand Breaks via ATM Signaling Pathway in Bovine Oocytes
por: Wang, Lili, et al.
Publicado: (2020)

RAG-induced DNA double-strand breaks signal through Pim2 to promote pre–B cell survival and limit proliferation
por: Bednarski, Jeffrey J., et al.
Publicado: (2012)

Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR
por: Dellaire, Graham, et al.
Publicado: (2006)

Chromatin modifications and DNA repair: beyond double-strand breaks
por: House, Nealia C. M., et al.
Publicado: (2014)

The Dynamic Behavior of Chromatin in Response to DNA Double-Strand Breaks
por: García Fernández, Fabiola, et al.
Publicado: (2022)

Transcriptional regulation and chromatin dynamics at DNA double-strand breaks
por: Min, Sunwoo, et al.
Publicado: (2022)

Efficacy of ATR inhibitors as single agents in Ewing sarcoma
por: Nieto-Soler, Maria, et al.
Publicado: (2016)

A Mathematical Model for the Detection Mechanism of DNA Double-Strand Breaks Depending on Autophosphorylation of ATM
por: Mouri, Kazunari, et al.
Publicado: (2009)

Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase
por: Köcher, Sabrina, et al.
Publicado: (2012)

The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair
por: Fenton, Amanda L., et al.
Publicado: (2013)

ATM Release at Resected Double-Strand Breaks Provides Heterochromatin Reconstitution to Facilitate Homologous Recombination
por: Geuting, Verena, et al.
Publicado: (2013)

Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop
por: Qi, Leilei, et al.
Publicado: (2022)

An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation
por: López-Contreras, Andres J., et al.
Publicado: (2012)

Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo
por: Rogakou, Emmy P., et al.
Publicado: (1999)

Chromatin Ubiquitination Guides DNA Double Strand Break Signaling and Repair
por: Kolobynina, Ksenia G., et al.
Publicado: (2022)

Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma: ATM, ATR and FA in lung carcinoma
por: Beumer, Jan H., et al.
Publicado: (2015)

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
por: Beucher, Andrea, et al.
Publicado: (2009)

ATM and ATR Activities Maintain Replication Fork Integrity during SV40 Chromatin Replication
por: Sowd, Gregory A., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_l5j760hl73hpn1i6morg3hvjur