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Loss of the proapoptotic protein, Bim, breaks B cell anergy
Although B cells that respond with high avidity to self-antigen are eliminated early in their development, many autoreactive B cells escape elimination and are tolerized later in their lives via anergy. Anergic B cells are unresponsive to antigen and die prematurely. It has been suggested that the p...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118238/ https://www.ncbi.nlm.nih.gov/pubmed/16520387 http://dx.doi.org/10.1084/jem.20051407 |