Immune responses and HIV: a little order from the chaos

HIV is evolution gone mad and bad. The virus infects a person and rapidly diversifies to become a huge swarm of viruses, each equipped differently to resist the onslaught of diverse T cells and antibodies. We can't expect to predict details of the struggle between virus and immunity, right? Wro...

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Detalles Bibliográficos
Autores principales: O'Connor, David H., Burton, Dennis R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118239/
https://www.ncbi.nlm.nih.gov/pubmed/16533889
http://dx.doi.org/10.1084/jem.20060216
Descripción
Sumario:HIV is evolution gone mad and bad. The virus infects a person and rapidly diversifies to become a huge swarm of viruses, each equipped differently to resist the onslaught of diverse T cells and antibodies. We can't expect to predict details of the struggle between virus and immunity, right? Wrong—maybe we can make some predictions, say two new landmark studies with potentially huge consequences for AIDS vaccine design.

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