Cargando…

Intensified and protective CD4(+) T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine

Current human immunodeficiency virus (HIV) vaccine approaches emphasize prime boost strategies comprising multiple doses of DNA vaccine and recombinant viral vectors. We are developing a protein-based approach that directly harnesses principles for generating T cell immunity. Vaccine is delivered to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Trumpfheller, Christine, Finke, Jennifer S., López, Carolina B., Moran, Thomas M., Moltedo, Bruno, Soares, Helena, Huang, Yaoxing, Schlesinger, Sarah J., Park, Chae Gyu, Nussenzweig, Michel C., Granelli-Piperno, Angela, Steinman, Ralph M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118242/ https://www.ncbi.nlm.nih.gov/pubmed/16505141 http://dx.doi.org/10.1084/jem.20052005

Ejemplares similares

DC-SIGN (CD209) Mediates Dengue Virus Infection of Human Dendritic Cells
por: Tassaneetrithep, Boonrat, et al.
Publicado: (2003)

In vivo targeting of HIV gag to dendritic cells in combination with poly ICLC is safe and immunogenic in healthy volunteers
por: Caskey, M, et al.
Publicado: (2012)

Strategy for Identifying Dendritic Cell-Processed CD4(+) T Cell Epitopes from the HIV Gag p24 Protein
por: Bozzacco, Leonia, et al.
Publicado: (2012)

APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection
por: Pion, Marjorie, et al.
Publicado: (2006)

Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves
por: Choi, Jae-Hoon, et al.
Publicado: (2009)

In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination
por: Bonifaz, Laura C., et al.
Publicado: (2004)

Fusion of Ubiquitin to HIV Gag Impairs Human Monocyte-Derived Dendritic Cell Maturation and Reduces Ability to Induce Gag T Cell Responses
por: Herath, Shanthi, et al.
Publicado: (2014)

In vivo targeting of protein antigens to dendritic cells using anti‐DEC‐205 single chain antibody improves HIV Gag specific CD4(+) T cell responses protecting from airway challenge with recombinant vaccinia‐gag virus
por: Ngu, Loveline N., et al.
Publicado: (2017)

Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors
por: Granelli-Piperno, Angela, et al.
Publicado: (1996)

A subset of dendritic cells induces CD4(+) T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo
por: Soares, Helena, et al.
Publicado: (2007)

Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice
por: Sela, Uri, et al.
Publicado: (2011)

Dendritic cells are the principal stimulators of the primary mixed leukocyte reaction in mice
por: Steinman, RM, et al.
Publicado: (1983)

Studies of the cell surface of mouse dendritic cells and other leukocytes
por: Nussenzweig, MC, et al.
Publicado: (1981)

Dendritic cells require a systemic type I interferon response to mature and induce CD4(+) Th1 immunity with poly IC as adjuvant
por: Longhi, M. Paula, et al.
Publicado: (2009)

Cytotoxic T cells both produce and respond to interleukin 2
por: Andrus, L, et al.
Publicado: (1984)

Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses
por: Boscardin, Silvia B., et al.
Publicado: (2006)

Intensifying Continuous Production of Gag-HA VLPs at High Cell Density Using Stable Insect Cells Adapted to Low Culture Temperature
por: Fernandes, Bárbara, et al.
Publicado: (2022)

Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo
por: Hawiger, Daniel, et al.
Publicado: (2001)

The interaction of HIV with dendritic cells: outcomes and pathways
por: Piguet, Vincent, et al.
Publicado: (2007)

Dendritic Cells in Tolerance and Immunity against Pathogens
por: Boscardin, Silvia Beatriz, et al.
Publicado: (2016)

Efficient Targeting of Protein Antigen to the Dendritic Cell Receptor DEC-205 in the Steady State Leads to Antigen Presentation on Major Histocompatibility Complex Class I Products and Peripheral CD8(+) T Cell Tolerance
por: Bonifaz, Laura, et al.
Publicado: (2002)

Unique Type I Interferon Responses Determine the Functional Fate of Migratory Lung Dendritic Cells during Influenza Virus Infection
por: Moltedo, Bruno, et al.
Publicado: (2011)

Classical Flt3L-dependent dendritic cells control immunity to protein vaccine
por: Anandasabapathy, Niroshana, et al.
Publicado: (2014)

Influenza Virus–induced Dendritic Cell Maturation Is Associated with the Induction of Strong T Cell Immunity to a Coadministered, Normally Nonimmunogenic Protein
por: Brimnes, Marie K., et al.
Publicado: (2003)

P19-26. Directing macaque immune responses with an anti-dendritic cell HIV Gag p24 fusion protein vaccine
por: Martinon, F, et al.
Publicado: (2009)

A study of proteases and protease-inhibitor complexes in biological fluids
por: Granelli-Piperno, A, et al.
Publicado: (1978)

The Dendritic Cell Receptor for Endocytosis, Dec-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II–Positive Lysosomal Compartments
por: Mahnke, Karsten, et al.
Publicado: (2000)

The Induction of Tolerance by Dendritic Cells That Have Captured Apoptotic Cells
por: Steinman, Ralph M., et al.
Publicado: (2000)

Dendritic Cells Induce a Subpopulation of IL-12Rβ2-Expressing Treg that Specifically Consumes IL-12 to Control Th1 Responses
por: Sela, Uri, et al.
Publicado: (2016)

Will the Making of Plasmacytoid Dendritic Cells in Vitro Help Unravel Their Mysteries?
por: Banchereau, Jacques, et al.
Publicado: (2000)

New insights into retroviral Gag–Gag and Gag–membrane interactions
por: Maldonado, José O., et al.
Publicado: (2014)

Dendritic cell maturation by innate lymphocytes: coordinated stimulation of innate and adaptive immunity
por: Münz, Christian, et al.
Publicado: (2005)

Immune Tolerance After Delivery of Dying Cells to Dendritic Cells In Situ
por: Liu, Kang, et al.
Publicado: (2002)

Dendritic Cell Mediated Delivery of Plasmid DNA Encoding LAMP/HIV-1 Gag Fusion Immunogen Enhances T Cell Epitope Responses in HLA DR4 Transgenic Mice
por: Simon, Gregory G., et al.
Publicado: (2010)

Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
por: Anandasabapathy, Niroshana, et al.
Publicado: (2011)

Antigen-Specific Inhibition of Effector T Cell Function in Humans after Injection of Immature Dendritic Cells
por: Dhodapkar, Madhav V., et al.
Publicado: (2001)

Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity
por: Matos, Ines, et al.
Publicado: (2013)

Circulating precursors of human CD1c(+) and CD141(+) dendritic cells
por: Breton, Gaëlle, et al.
Publicado: (2015)

Gag-Gag Interactions Are Insufficient to Fully Stabilize and Order the Immature HIV Gag Lattice
por: Saha, Ipsita, et al.
Publicado: (2021)

New Insights into HTLV-1 Particle Structure, Assembly, and Gag-Gag Interactions in Living Cells
por: Fogarty, Keir H., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_l6nvpmtr7oj85nvlvlr3b0q3c3