Cargando…

Regulatory T cells inhibit stable contacts between CD4(+) T cells and dendritic cells in vivo

Regulatory T (T reg) cells exert powerful down-modulatory effects on immune responses, but it is not known how they act in vivo. Using intravital two-photon laser scanning microscopy we determined that, in the absence of T reg cells, the locomotion of autoantigen-specific T cells inside lymph nodes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tadokoro, Carlos E., Shakhar, Guy, Shen, Shiqian, Ding, Yi, Lino, Andreia C., Maraver, Antonio, Lafaille, Juan J., Dustin, Michael L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118249/ https://www.ncbi.nlm.nih.gov/pubmed/16533880 http://dx.doi.org/10.1084/jem.20050783

Ejemplares similares

Interleukin 2 Signaling Is Required for CD4(+) Regulatory T Cell Function
por: Furtado, Gláucia C., et al.
Publicado: (2002)

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo
por: Darrasse-Jèze, Guillaume, et al.
Publicado: (2009)

TCR-dependent differentiation of thymic Foxp3(+) cells is limited to small clonal sizes
por: Leung, Monica W.L., et al.
Publicado: (2009)

Human CD4(+)CD25(+) Regulatory, Contact-dependent T Cells Induce Interleukin 10–producing, Contact-independent Type 1-like Regulatory T Cells
por: Dieckmann, Detlef, et al.
Publicado: (2002)

Ex Vivo Isolation and Characterization of Cd4(+)Cd25(+) T Cells with Regulatory Properties from Human Blood
por: Dieckmann, Detlef, et al.
Publicado: (2001)

Resident CD141 (BDCA3)(+) dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation
por: Chu, Chung-Ching, et al.
Publicado: (2012)

MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells
por: Oh, Jaehak, et al.
Publicado: (2013)

Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo
por: Yadav, Mahesh, et al.
Publicado: (2012)

Human Dendritic Cells Activated by TSLP and CD40L Induce Proallergic Cytotoxic T Cells
por: Gilliet, Michel, et al.
Publicado: (2003)

CD103(+) pulmonary dendritic cells preferentially acquire and present apoptotic cell–associated antigen
por: Desch, A. Nicole, et al.
Publicado: (2011)

Definition of target antigens for naturally occurring CD4(+) CD25(+) regulatory T cells
por: Nishikawa, Hiroyoshi, et al.
Publicado: (2005)

Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo
por: Swiecki, Melissa, et al.
Publicado: (2011)

Infectious Tolerance: Human CD25(+) Regulatory T Cells Convey Suppressor Activity to Conventional CD4(+) T Helper Cells
por: Jonuleit, Helmut, et al.
Publicado: (2002)

Follicular Dendritic Cells Specifically Express the Long CR2/CD21 Isoform
por: Liu, Yong-Jun, et al.
Publicado: (1997)

Increased frequencies of CD4(+)CD25(high) regulatory T cells in acute dengue infection
por: Lühn, Kerstin, et al.
Publicado: (2007)

Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Can Regulate Dendritic Cell–induced Activation and Cytotoxicity of CD8(+) T Cells Independently of CD4(+)T Cell Help
por: McCoy, Kathy D., et al.
Publicado: (1999)

The Immune Regulatory Function of Lymphoproliferative Double Negative T Cells In Vitro and In Vivo
por: Ford, Megan S., et al.
Publicado: (2002)

CD11c(lo)B220(+) interferon-producing killer dendritic cells are activated natural killer cells
por: Vosshenrich, Christian A.J., et al.
Publicado: (2007)

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
por: Deaglio, Silvia, et al.
Publicado: (2007)

Interleukin 12–dependent Interferon γ Production by CD8α(+)Lymphoid Dendritic Cells
por: Ohteki, Toshiaki, et al.
Publicado: (1999)

B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8(−) dendritic cells require the intramembrane endopeptidase SPPL2A
por: Bergmann, Hannes, et al.
Publicado: (2013)

Cd47 (Integrin-Associated Protein) Engagement of Dendritic Cell and Macrophage Counterreceptors Is Required to Prevent the Clearance of Donor Lymphohematopoietic Cells
por: Blazar, Bruce R., et al.
Publicado: (2001)

Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4(+) T cell–dendritic cell interactions
por: Moalli, Federica, et al.
Publicado: (2014)

Human Cd25(+)Cd4(+) T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function
por: Levings, Megan K., et al.
Publicado: (2001)

Cd4(+)Cd25(+) Immune Regulatory Cells Are Required for Induction of Tolerance to Alloantigen via Costimulatory Blockade
por: Taylor, Patricia A., et al.
Publicado: (2001)

The CD8α(+) Dendritic Cell Is Responsible for Inducing Peripheral Self-Tolerance to Tissue-associated Antigens
por: Belz, Gabrielle T., et al.
Publicado: (2002)

MHC Class II Expression Restricted to CD8α(+) and CD11b(+) Dendritic Cells Is Sufficient for Control of Leishmania major
por: Lemos, Maria P., et al.
Publicado: (2004)

Thrombospondin 1 Is an Autocrine Negative Regulator of Human Dendritic Cell Activation
por: Doyen, Virginie, et al.
Publicado: (2003)

Immature Dendritic Cells Acquire Cd8(+)Cytotoxic T Lymphocyte Priming Capacity upon Activation by T Helper Cell–Independent or–Dependent Stimuli
por: Schuurhuis, Danita H., et al.
Publicado: (2000)

Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4(+) T cells after FcγRII-mediated uptake
por: Benitez-Ribas, Daniel, et al.
Publicado: (2006)

Cd11c(+)B220(+)Gr-1(+) Cells in Mouse Lymph Nodes and Spleen Display Characteristics of Plasmacytoid Dendritic Cells
por: Nakano, Hideki, et al.
Publicado: (2001)

TGF-β1 maintains suppressor function and Foxp3 expression in CD4(+)CD25(+) regulatory T cells
por: Marie, Julien C., et al.
Publicado: (2005)

Defective Suppressor Function of Human CD4(+) CD25(+) Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II
por: Kriegel, Martin A., et al.
Publicado: (2004)

The Role of Aquaporins in Dendritic Cell Macropinocytosis
por: de Baey, Annegret, et al.
Publicado: (2000)

CD28-independent Induction of T Helper Cells and Immunoglobulin Class Switches Requires Costimulation by the Heat-stable Antigen
por: Wu, Yan, et al.
Publicado: (1998)

Dendritic Cells Cross-Present Latency Gene Products from Epstein-Barr Virus–Transformed B Cells and Expand Tumor-Reactive Cd8(+) Killer T Cells
por: Subklewe, Marion, et al.
Publicado: (2001)

GM-CSF–dependent, CD103(+) dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization
por: King, Irah L., et al.
Publicado: (2010)

NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4(+) T lymphocytes by CD4(+) CD25(+) regulatory T cells
por: Bopp, Tobias, et al.
Publicado: (2005)

Immunologic Self-Tolerance Maintained by Cd25(+)Cd4(+)Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
por: Takahashi, Takeshi, et al.
Publicado: (2000)

Tolerogenic function of Blimp-1 in dendritic cells
por: Kim, Sun Jung, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_1kjcri730amjpfuogmmoldoilf