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In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules

Endoplasmic reticulum (ER)-associated aminopeptidase (ERAP)1 has been implicated in the final proteolytic processing of peptides presented by major histocompatibility complex (MHC) class I molecules. To evaluate the in vivo role of ERAP1, we have generated ERAP1-deficient mice. Cell surface expressi...

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Detalles Bibliográficos
Autores principales:	Yan, Jingbo, Parekh, Vrajesh V., Mendez-Fernandez, Yanice, Olivares-Villagómez, Danyvid, Dragovic, Srdjan, Hill, Timothy, Roopenian, Derry C., Joyce, Sebastian, Van Kaer, Luc
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118255/ https://www.ncbi.nlm.nih.gov/pubmed/16505142 http://dx.doi.org/10.1084/jem.20052271

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