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Structure and binding kinetics of three different human CD1d–α-galactosylceramide–specific T cell receptors
Invariant human TCR Vα24-Jα18(+)/Vβ11(+) NKT cells (iNKT) are restricted by CD1d–α-glycosylceramides. We analyzed crystal structures and binding characteristics for an iNKT TCR plus two CD1d–α-GalCer–specific Vβ11(+) TCRs that use different TCR Vα chains. The results were similar to those previously...
Autores principales: | Gadola, Stephan D., Koch, Michael, Marles-Wright, Jon, Lissin, Nikolai M., Shepherd, Dawn, Matulis, Gediminas, Harlos, Karl, Villiger, Peter M., Stuart, David I., Jakobsen, Bent K., Cerundolo, Vincenzo, Jones, E. Yvonne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118257/ https://www.ncbi.nlm.nih.gov/pubmed/16520393 http://dx.doi.org/10.1084/jem.20052369 |
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