Structure and binding kinetics of three different human CD1d–α-galactosylceramide–specific T cell receptors

Invariant human TCR Vα24-Jα18(+)/Vβ11(+) NKT cells (iNKT) are restricted by CD1d–α-glycosylceramides. We analyzed crystal structures and binding characteristics for an iNKT TCR plus two CD1d–α-GalCer–specific Vβ11(+) TCRs that use different TCR Vα chains. The results were similar to those previously...

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Detalles Bibliográficos
Autores principales: Gadola, Stephan D., Koch, Michael, Marles-Wright, Jon, Lissin, Nikolai M., Shepherd, Dawn, Matulis, Gediminas, Harlos, Karl, Villiger, Peter M., Stuart, David I., Jakobsen, Bent K., Cerundolo, Vincenzo, Jones, E. Yvonne
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118257/
https://www.ncbi.nlm.nih.gov/pubmed/16520393
http://dx.doi.org/10.1084/jem.20052369

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