A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition

Little is known regarding the basis for selection of the semi-invariant αβ T cell receptor (TCR) expressed by natural killer T (NKT) cells or how this mediates recognition of CD1d–glycolipid complexes. We have determined the structures of two human NKT TCRs that differ in their CDR3β composition and...

Descripción completa

Detalles Bibliográficos
Autores principales: Kjer-Nielsen, Lars, Borg, Natalie A., Pellicci, Daniel G., Beddoe, Travis, Kostenko, Lyudmila, Clements, Craig S., Williamson, Nicholas A., Smyth, Mark J., Besra, Gurdyal S., Reid, Hugh H., Bharadwaj, Mandvi, Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118261/
https://www.ncbi.nlm.nih.gov/pubmed/16505140
http://dx.doi.org/10.1084/jem.20051777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118261/
https://www.ncbi.nlm.nih.gov/pubmed/16505140
http://dx.doi.org/10.1084/jem.20051777

Ejemplares similares