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CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40
Secondary T cell responses are enhanced because of an expansion in numbers of antigen-specific (memory) cells. Using major histocompatibility complex class II tetramers we have tracked peptide-specific endogenous (non–T cell receptor transgenic) CD4 memory T cells in normal and in costimulation-defi...
Autores principales: | MacLeod, Megan, Kwakkenbos, Mark J., Crawford, Alison, Brown, Sheila, Stockinger, Brigitta, Schepers, Koen, Schumacher, Ton, Gray, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118277/ https://www.ncbi.nlm.nih.gov/pubmed/16549596 http://dx.doi.org/10.1084/jem.20050711 |
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