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Endogenous IRBP can be dispensable for generation of natural CD4(+)CD25(+) regulatory T cells that protect from IRBP-induced retinal autoimmunity

Susceptibility to experimental autoimmune uveitis (EAU), a model for human uveitis induced in mice with the retinal antigen interphotoreceptor retinoid-binding protein (IRBP), is controlled by “natural” CD4(+)CD25(+) regulatory T (T reg) cells. To examine whether endogenous expression of IRBP is nec...

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Detalles Bibliográficos
Autores principales:	Grajewski, Rafael S., Silver, Phyllis B., Agarwal, Rajeev K., Su, Shao-Bo, Chan, Chi-Chao, Liou, Gregory I., Caspi, Rachel R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118294/ https://www.ncbi.nlm.nih.gov/pubmed/16585264 http://dx.doi.org/10.1084/jem.20050429

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