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Dysregulated T cell expression of TIM3 in multiple sclerosis

T cell immunoglobulin- and mucin domain–containing molecule (TIM)3 is a T helper cell (Th)1–associated cell surface molecule that regulates Th1 responses and promotes tolerance in mice, but its expression and function in human T cells is unknown. We generated 104 T cell clones from the cerebrospinal...

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Detalles Bibliográficos
Autores principales:	Koguchi, Ken, Anderson, David E., Yang, Li, O'Connor, Kevin C., Kuchroo, Vijay K., Hafler, David A.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118310/ https://www.ncbi.nlm.nih.gov/pubmed/16754722 http://dx.doi.org/10.1084/jem.20060210

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