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IFNγ-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice

Approximately 20% of human cancers are estimated to develop from chronic inflammation. Recently, the NF-κB pathway was shown to play an essential role in promoting inflammation-associated cancer, but the role of the JAK/STAT pathway, another important signaling pathway of proinflammatory cytokines,...

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Detalles Bibliográficos
Autores principales: Hanada, Toshikatsu, Kobayashi, Takashi, Chinen, Takatoshi, Saeki, Kazuko, Takaki, Hiromi, Koga, Keiko, Minoda, Yasumasa, Sanada, Takahito, Yoshioka, Tomoko, Mimata, Hiromitsu, Kato, Seiya, Yoshimura, Akihiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118311/
https://www.ncbi.nlm.nih.gov/pubmed/16717119
http://dx.doi.org/10.1084/jem.20060436