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IFNγ-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice
Approximately 20% of human cancers are estimated to develop from chronic inflammation. Recently, the NF-κB pathway was shown to play an essential role in promoting inflammation-associated cancer, but the role of the JAK/STAT pathway, another important signaling pathway of proinflammatory cytokines,...
Autores principales: | Hanada, Toshikatsu, Kobayashi, Takashi, Chinen, Takatoshi, Saeki, Kazuko, Takaki, Hiromi, Koga, Keiko, Minoda, Yasumasa, Sanada, Takahito, Yoshioka, Tomoko, Mimata, Hiromitsu, Kato, Seiya, Yoshimura, Akihiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118311/ https://www.ncbi.nlm.nih.gov/pubmed/16717119 http://dx.doi.org/10.1084/jem.20060436 |
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