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The Eδ enhancer controls the generation of CD4(−)CD8(−) αβTCR-expressing T cells that can give rise to different lineages of αβ T cells
It is well established that the pre–T cell receptor for antigen (TCR) is responsible for efficient expansion and differentiation of thymocytes with productive TCRβ rearrangements. However, Ptcra- as well as Tcra-targeting experiments have suggested that the early expression of Tcra in CD4(−)CD8(−) c...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118313/ https://www.ncbi.nlm.nih.gov/pubmed/16754716 http://dx.doi.org/10.1084/jem.20051711 |