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Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis

Caspase-1 is activated by a variety of stimuli after the assembly of the “inflammasome,” an activating platform made up of a complex of the NOD-LRR family of proteins. Caspase-1 is required for the secretion of proinflammatory cytokines, such as interleukin (IL)-1β and IL-18, and is involved in the...

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Detalles Bibliográficos
Autores principales:	Lara-Tejero, Maria, Sutterwala, Fayyaz S., Ogura, Yasunori, Grant, Ethan P., Bertin, John, Coyle, Anthony J., Flavell, Richard A., Galán, Jorge E.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118315/ https://www.ncbi.nlm.nih.gov/pubmed/16717117 http://dx.doi.org/10.1084/jem.20060206

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