A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression

Toll-like receptors (TLRs) function as primary sensors that elicit coordinated innate immune defenses through recognition of microbial products and induction of immune and proinflammatory genes. Here we report the identification and biological characterization of a lipopolysaccharide (LPS)-like mole...

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Detalles Bibliográficos
Autores principales: Macagno, Annalisa, Molteni, Monica, Rinaldi, Andrea, Bertoni, Francesco, Lanzavecchia, Antonio, Rossetti, Carlo, Sallusto, Federica
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118317/
https://www.ncbi.nlm.nih.gov/pubmed/16717116
http://dx.doi.org/10.1084/jem.20060136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118317/
https://www.ncbi.nlm.nih.gov/pubmed/16717116
http://dx.doi.org/10.1084/jem.20060136

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